About
We've reinvented how biologic drugs are made
Lumen's patented technology allows us to use the well-known food algae spirulina to deliver therapeutic proteins.
Patented technology with unlimited potential
The astonishingly high cost of traditional drug development meant that using orally delivered biologics to address therapeutic targets in the GI tract and other topical sites wasn’t commercially viable. That’s no longer true. Lumen’s patented biologic drug platform shortens the development process, reduces costs and risks, and accelerates time-to-market, making us the first company to make orally delivered antibody drugs commercially viable.
$84M
invested to date
33
issued patents
19
other patents pending
01
Formation
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Incorporated April 2017
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Foundational IP, core team, assets acquired from two predecessor entities
02
Funding
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$84 million in platform investment to date
03
Intellectual Property
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25 issued patents
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Issued patents include broad, composition-of-matter claims covering engineered spirulina, recognition that Lumen was the first in the world to engineer spirulina
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Broad continuation claims cover all long-term contemplated products
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17 other patents pending
04
Physical Capabilities
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77 FTEs, including >25 with MDs, PhDs, and other post-graduate degrees
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Fully integrated, on-premise, dedicated cGMP production facility with capacity for several kilograms of drug product per week
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Full-time clinical operations and FDA regulatory affairs team
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High-throughput strain engineering facility
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Advanced protein engineering and optimization
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Large-scale AI/machine learning–enabled yield optimization facility
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On-premise antibody selection and optimization capabilities (hit to the lead clinic), including advanced in silicoprotein engineering and optimization
A typical biosciences company assembles a group of individuals with a relatively narrow set of skills within a discipline and goes about its business. At Lumen, it’s the particularity of our key scientists’ individual skills and experiences—and the interplay among them—that have been a catalyst to discover and exploit the potential of this new platform organism. As a true platform company, we’re able to create our own portfolio of commercially viable biologic therapies, while establishing a foundation upon which an entirely new generation of scientific discoveries and therapies will be brought to market.
It’s widely known that the most creative and successful teams are drawn from disparate fields. Building Lumen’s platform from the foundation up made this natural for us, and it’s a privilege to work with leaders from such diverse backgrounds.
Brian Finrow
Expertise. Ingenuity. Execution.
We’ve assembled a talented group of leaders with deep expertise in synthetic biology, protein design, immunology, photobioreactor engineering and cell physiology, each with the vision and skills needed to achieve our mission.
Leadership
Brian Finrow
Co-Founder and Chief Executive Officer
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Adaptive Biotechnologies
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AltAir Fuels
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Cooley, LLP
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Harvard Law School
Jim Roberts
Co-Founder and Chief Scientific Officer
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Director, Fred Hutch Cancer Research Center, Basic Sciences Division
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Former HHMI Investigator
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Co-inventor of a mammalian cell
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Transformation technology
Craig Behnke
EVP, Production/Development
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Sapphire Energy
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Takeda Pharmaceuticals
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University of Washington, PhD, Biochemistry
Eric Orse
Chief Financial Officer
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Varolii Corp
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eCharge Corporation
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Price Waterhouse
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Veteran VC-backed tech company and early stage CFO
John Morrow
COO and General Counsel
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Apptio
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Verafore
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Paymentus
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Venture Law Group / Heller Ehrman
Barry Stoddard
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Member, Fred Hutch Cancer Research Center, Basic Sciences Division
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Structural biology and protein design
Richard Guerrant
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Founding Director, Center for Global Health
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Professor of International Medicine, University of Virginia, Division of Infectious Diseases and International Health
James Lord
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Assistant Member, Benaroya Research Institute
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Gastroenterology, University of Washington School of Medicine
George McDonald
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Professor Emeritus, Fred Hutch Cancer Research Center, Clinical Research Division, Gastroenterology
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Professor Emeritus, University of Washington Medical School
Jim Nataro
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Professor and Chair, Pediatrics
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University of Virginia School of Medicine
Scott Hensley
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Associate Professor of Microbiology Penn Institute for Immunology
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University of Pennsylvania School of Medicine
Vincent Fischetti
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Professor and Head of the Laboratory of Bacterial Pathogenesis and Immunology, Rockefeller University in New York
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Microbiology, New York University
Brian Finrow
CEO & Co-Founder, Lumen
Jim Roberts, MD, PhD
CSO & Co-Founder, Lumen
Rob Carlson
Bioeconomy Capital
Mark Litton
Athira Pharma
Marcos Milla
Samsara BioCapital
Erik Anderson
WestRiver Group
Inspired by science. Driven by results.
We are always on the lookout for creative, motivated people who want to make a difference.
See open positions