Accelerating cures. Expanding access.
Lumen’s unique drug development environment radically reduces the time and investment required for biologic drug development.
Doing What’s Never
Been Done Before
Daily, Oral
Biologic Drugs
We develop and manufacture biotherapeutics for disease targets that have been inaccessible, because of the astonishingly high cost of traditional biomanufacturing methods. Now, for the first time, Lumen can make antibodies and other biologics at a cost that allows for daily, oral and topical delivery.
Our current programs target diseases with well proven therapeutic mechanisms of action, and whose unmet medical need is obvious.
How It Works
01
The Organism
Being extraordinarily high in soluble protein (>60%), spirulina cells are able to express far higher amounts tof therapeutic proteins than any other food crop.
02
Bio Engineering
A gene encoding the therapeutic molecule (for example, an antibody protein or cytokine) is introduced into the spirulina chromosome.
03
Production
The production system requires only water, salt, CO2, and light, so it is cheap and massively scalable. The entire biomass is simply spray dried to a fine powder.
04
Delivery
For G.I. targets, this powder is packed into capsules or tablets. Most are shelf-stable at room temperature which makes distribution cheap and easy.
Better Tools Yield
Better Outcomes
Time, risk, and money are the three wild cards of drug development. Lumen’s unique drug development environment improves all three because of the proven safety of the expression host (spirulina) and the speed at which we’re able to safely develop and manufacture new biologics.
The long safety records of both spirulina and orally delivered protein therapeutics make our drugs less risky for study volunteers and patients. And, post-approval, our patented technology enables us to manufacture orally delivered biologic drugs at a cost per gram two to three orders of magnitude lower than traditional biomanufacturing.
Taken together, these advantages enable new solutions for diseases that have long frustrated researchers hampered by the limitations of conventional drug development.
Our patented technology
enables us to manufacture orally delivered biologic drugs at a cost two to three orders of magnitude lower than conventional bio manufacturing.