We’ve reinvented how biologic drugs are made
Lumen’s patented technology allows us to use the well-known food algae spirulina to make and orally deliver therapeutic proteins.
Patented Technology
With Unlimited Potential
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>$84M
Invested To Date
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33
Issued Patents
Formation
- Incorporated April 2017
- Foundational IP, core team, assets
Funding
- > $84 million in platform investment to date
- The innovative technology has attracted record non-dilutive funding nearly a dozen U.S. federal agencies, the Gates Foundation, and other leading philanthropies focused on human and animal health
- Collaboration funding from leading global biopharmaceutical companies
Physical Capabilities
- 95 FTEs, including >47 with MDs, PhDs, and other post-graduate degrees
- Fully integrated, dedicated cGMP production facility with capacity for > 15 kilograms of GMP drug substance per week
- Full-time clinical operations and FDA regulatory affairs team
- High-throughput strain engineering facility
- Advanced protein engineering and optimization
- Large-scale AI/machine learning–enabled yield optimization
- On-premise antibody selection and optimization capabilities (hit-to-lead clinic), including advanced in silicoprotein engineering and optimization
Intellectual Property
- 33 issued patents
- Issued patents include broad, composition-of-matter claims covering engineered spirulina, recognition that Lumen was the first in the world to engineer this microbe
- Broad continuation claims cover all long-term contemplated products
- 17 other patents pending
A conventional biopharma company typically builds its team with a fairly narrow set of skills within a single discipline—most often a single disease area. Most drug development happens through contractors like CROs and CDMOs.
Lumen is different.
Like the bold visionaries who exploited the first two waves of cell-engineering breakthroughs (Genentech with E. coli in the 1970s; Amgen with mammalian cells in the 1990s), Lumen is completely vertically integrated. From our facilities in Seattle’s Fremont neighborhood, our team directly executes nearly all aspects of the drug development process—from hit-to-lead discovery and protein engineering through GMP manufacturing and clinical development.
Close team integration under one roof lets us move much more quickly and efficiently, part of why our development costs and timelines are a small fraction of those of other biopharma companies. It’s also a lot more fun, with big new discoveries happening almost every week.
“Working for Lumen is an exciting opportunity to grow your skillset while also contributing to a technology that can really make a difference and impact so many people.”
Principal Scientist
Expertise. Ingenuity. Execution.
We’ve assembled a talented group of leaders with deep expertise in synthetic biology, protein design, immunology, photobioreactor engineering, and cell physiology, each with the vision and skills needed to achieve our mission.
Leadership Team
Scientific Advisors
Barry Stoddard
- Member, Fred Hutch Cancer Center, Basic Sciences Division
- Structural biology and protein design
Jim Nataro
- Professor and Chair, Pediatrics, University of Virginia School of Medicine
James Lord
- Assistant Member, Benaroya Research Institute Gastroenterology, University of Washington School of Medicine
Richard Guerrant
- Founding Director, Center for Global Health
- Professor of International Medicine, University of Virginia, Division of Infectious Diseases and International Health
Scott Hensley
- Associate Professor of Microbiology Penn Institute for Immunology
- University of Pennsylvania School of Medicine
Alex DePaoli
- Formerly at Amgen
- Practicing Diabetes & Metabolism Endocrinologist
Steven Heymsfield
- Professor Pennington Biomedical Research Center
- Leading metabolism researcher
Davis Maggs
- Formerly at Amylin
- Adjunct Faculty Member of the School of Medicine at The University of Texas Health Science Center
Board Of Directors
Brian Finrow
CEO & Co-Founder, Lumen
Jim Roberts, MD, PhD
CSO & Co-Founder, Lumen
Rob Carlson
Bioeconomy Capital
Mark Litton
Athira Pharma
Marcos Milla
Samsara BioCapital
Erik Anderson
WestRiver Group
Funding Organizations
Lumen’s technology presents a new way to target diseases that conventional biopharma technologies have failed to solve, so we are thankful for the significant funding support we have received from a range of private foundations, NGOs and government agencies.
Research Collaborators
In many cases the cutting edge of discovery is carried out at non-commercial
research institutions like universities and government labs. We are honored
to be working closely with so many are leaders in their respective fields.
Brian Finrow
Co-Founder, Chairman and Chief Executive Officer
Brian Finrow brings the skills and experience of a lawyer to a position that, in the biotech world, is more typically occupied by a scientist. This is essential to an enterprise like Lumen, which is rethinking drug development from the ground up to emphasize speed, efficiency and ease of delivery, and whose approach is so innovative that traditional ways of thinking about IP and regulatory pathways oftentimes do not apply.
Prior to co-founding Lumen, Brian oversaw complex negotiations with various major biopharma companies and managed IP strategy for Adaptive Biotechnologies, where he was Senior Vice President and General Counsel. As senior attorney at the law firm Cooley LLP, his practice focused on equity financing and M&A transactions, and negotiating complex biotech licensing and collaboration deals. With over 15 years of legal and commercial experience at these market-leading, innovative firms, he is well positioned to develop creative, win-win deal structures with other organizations.
Harvard Law School, JD
Harding University, BS, Public Administration
Harding University, BA, Political Science
Jim Roberts
Co-Founder and Chief Scientific Officer
Jim Roberts’s career trajectory aligns precisely with the pioneering breakthroughs in the field of biotechnology. Time spent in the Axel Lab during his student years at Columbia University overlapped with the discovery of gene transfer methods for mammalian cells, and helped lay the groundwork for an involvement with the Fred Hutchinson Cancer Research Center that now spans more than three decades.
Ten years as an Investigator at the prestigious Howard Hughes Medical Institute in the 1990s and early 2000s, followed by six years as Director of Basic Sciences at the Hutch, combined with a career-long involvement in the field of cell cycle and cancer biology to instill a fine-grained grasp of both the importance of a sound conceptual foundation and the disadvantages of a vision that’s too narrowly defined. Of special significance to Lumen, Jim’s front-row seat on the development of the field provides a kind of institutional memory that dates back long before the company’s actual founding.
Columbia University Vagelos College of Physicians and Surgeons, MD, PhD, Medicine/Biochemistry
Amherst College, BA, Biology
Craig Behnke
EVP, Production/Development
Craig’s unusual intersection of expertise in drug development and microbiology is a precise match for Lumen’s core science and its ability to deliver novel biologic drugs to patients at unprecedented scale. He began his career in protein engineering and X-ray crystallography—both critical tools for the development of antibodies—before transitioning to the development of small-molecule drug discovery, and then finally to finding industrial applications for photosynthetic microbes.
He has played important roles at various startups, including Sapphire Energy (as head of R&D) and Syrrx (acquired by Takeda Pharmaceuticals), reflecting not only the scientific firepower he brings to the table but also his management expertise. Both assets are invaluable to Lumen’s mission to make antibody drugs available to mass-market applications for the first time.
University of Washington, PhD, Biochemistry
Kansas State University, MS, Biochemistry
Kansas State University, BS, Biochemistry/Microbiology
Eric Orse
Chief Financial Officer
Eric’s diverse management skills result from a wide range of industries, including high tech, real estate, manufacturing, healthcare, transportation and retail. As a CFO, he has overseen companies ranging in size from 10 to 500 employees, managing early stage growth companies to mature multi-generational companies.
Eric brings integrity and transparency to his role, as well as experience with early to mid stage companies and the need for hands-on engagement through all the stages of growth. Eric is a CPA(inactive) and worked in both the Audit Group and Restructuring Group at Price Waterhouse.
Seattle University, MBA, Finance/Business Management
Seattle University, BA, Accounting
Carl Mason
VP, Clinical
Carl Mason’s career path and experience is well suited for Lumen Bioscience. He joins Lumen following six years as Medical Director at Parexel, an industry leading clinical research organization. Previously, he had fourteen years of clinical research experience overseas as Chief of the Department of Enteric Diseases at the Armed Forced Research Institute of Medical Sciences (AFRIMS) in Bangkok, Thailand. Carl executed projects on diarrheal diseases in Asia funded by the US Department of Defense, the National Institute of Allergy and Infectious Disease (NIAID), and the Bill and Melinda Gates Foundation.
John Hopkins Bloomberg School of Public Health, MPH, Epidemiology
Lewis Katz School of Medicine at Temple University, MD, Medicine
Cornell University College of Art and Sciences, AB, Chemistry
John Morrow
COO and General Counsel
John brings extensive experience leading legal, corporate development, operational, financial and business functions at critical transformational moments to Lumen. John has been a key team member in creating billions of dollars in equity value via two IPOs and two $1+ billion M&A transactions with an array of leading investors. John has also led 15 buy-side M&A transactions and a significant number of other capital markets transactions.
John’s experience includes operational and legal roles spanning all G&A functions at market leading global technology companies such as Apptio, Vertafore and Paymentus. Earlier in his career John was a partner at Heller Ehrman and a lawyer with Venture Law Group where he represented life sciences companies such as Seagen, Xcyte Therapies, Scout Medical and others. John is valued for his unique combination of legal, business, management and financial skills that make him a valued consigliere to management teams and Boards.
Steve Landas
VP & Controller
Steve brings over twenty years of financial leadership and experience to Lumen, which includes development stage companies to a Fortune 500 company. Prior to Joining Lumen, Steve held increasing roles of responsibilities including serving as Vice President of Finance and Corporate Controller at Cascadian Therapeutics, a publicly traded oncology company that was acquired by Seattle Genetics in 2018. While at Cascadian, he was instrumental in building out the finance team and financial systems to scale with the company’s growth and reporting requirements. Steve also served in various positions at Seattle Genetics, Xcyte Therapies, Chiron, and PathoGenesis.
Steve received a B.A in Business Administration with a concentration in accounting from the University of Washington’s Foster School of Business.
Karina Mounivong
VP, Human Resources
Karina has over 15 years of experience in Human Resources working in software and biotechnology companies of various sizes. Prior to joining Lumen, Karina was the VP, Global HR for Nintex, a software company that specializes in process management and automation workflow. While at Nintex, Karina was a part of scaling the company through organic and inorganic growth, completed five acquisitions and integrations in her time there, and was a part of building a great company culture. Karina has also worked at Varolii Corporation and started her HR career in biotech at ZymoGenetics, Inc.
Karina received her B.A. in Interdisciplinary Studies, Community Psychology, and a Minor in Human Rights from University of Washington
Kole Krieger
VP, Business Development
Kole’s in-depth experience and vast network within the biotech and pharmaceutical industry is perfectly aligned to his role of Vice President of Business Development at Lumen Bioscience. Prior to joining Lumen, Kole was the Vice President of Business Development for Absci Bio (NASDAQ:ABSI), a publicly traded AI drug and target discovery company utilizing synthetic biology. While at Absci, Kole led business development and sales efforts. During his five-year tenure, he created long-term partnerships with biotech and pharma companies that resulted in multiple historic licensing deals, enabling the growth of the company from 15 to 250+ employees. In 2019, Kole was selected by the Portland Business Journal as the region’s ‘Rainmaker’, an award given to the top business sales professional.
Linfield University, BA, Finance